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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074a4ca1cd335ce61130003039eed4df31bcd88fd064ecf5a722d9345b9f6158' 
  AND token = 'PYvNLPbMwLMokNt2ThVFYhW+mF6TV0ddqyHeoX3K0QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}