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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1a25b27b1a64b119847681b35df106ad8f21111e1e0e0f53f8bee482857f2d' 
  AND token = 'JOPAacPom6u/SxFe7buGTwKUK1/M/PmauLabOb6ugzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}