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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946274a7a89d8a772cdf251dc9a3be563256360925084b7115c41142940fc742' 
  AND token = '2+vOOqcFqEJRkBGRcpRz4HhRasuMqzp2GTrDbORoNns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}