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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbc0222c808bef4816c4bfc920425ff019e4f76013f211003bacb433e2bd551a' 
  AND token = '4wHW4rdcOHmI35xS03CZ1X2nckY7uHCORIUzTxQA03A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}