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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288ac3dcec186a706e47e597b443c9be3622d10f713b11b84bf05d497bea21c2' 
  AND token = 'oP9SNEtJBPMUjvi9K6f+vi7QWmljAxNIJX5zyHQ6QA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}