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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e874ec9cf0423bc4c0ab3cb70ff783bd6e6194d702cd845f0f8257b0429d5ed4' 
  AND token = 'nk95Vptw4G3c2lxfsxFEgKpAvhWwzMHBrZsN0ZwkKoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}