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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd58b27de1637be29f7209079dec10a8aed905583eafa810e198955c1f181697' 
  AND token = 'Ci7qylT677w7hV5ZTm6ol0Bckv36qDQP8fSkS/Bnxso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}