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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c39c96a9f1fc29500fe7452ef8dd54c9c5a312c913dd74755f6519f712994c' 
  AND token = 'PlFCVruXO3X7+kIgzS5QI25LKfbyPlzo1yZrZn8yS3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}