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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3efb2c6a18c41ebba1e1dcf3acc0b005bee09e2d60c4bc04170dd27947e51241' 
  AND token = 'C/wozvwwgqTmf6tDgPwVftGDgZwvt4SLQV3qS0vVuS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}