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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db150b20f8864345f85103bf04aa663381b52ade8748a544087b2567585d5e99' 
  AND token = 'JxTet1pp49q47pC1H7WE6BfzhqKn5TWhnPiH//EtWAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}