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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5498b410c9faae7aea5b0068b41564b41dabf4641e1acedb56111aa4a4d9f776' 
  AND token = 'dMZFhIibDJfAbjHrwYa+KXzMDIr+SDGKPzVFWhF9/bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}