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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b008025a9b4cd5ab735f5d7beeb883b8d627687333916557fc8766851b0e840f' 
  AND token = '1nn2fJrHUbl0OLidaWVvCKTWTuLD2LHJqZOgv6qEJME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}