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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363c246fb3757db42cf35596e0274af848a6f016c4b7ced6b3fe3bafcd1efab7' 
  AND token = 'kcTyqEM37r1IHYPRNptlVtBRn+94gK4e14Mdjd2LnHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}