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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2873c74f2bdb4f82e3e52696fb48f559b96db6e9f88594d6126755345327b35' 
  AND token = '6B/RIAeFMox+RBbaSR8i2E9gkcYeuI/pOpk4uoRJjfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}