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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5361627cfd6976670cfa9d06cb5743f244b357c7d6558279b55446aa751981' 
  AND token = 'AbeEXc2yuq8Bsx0a5eyAnQl108oI/0j1I+C1HHDhvWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}