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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45496d8d576c06a676f4243a250ad47099fdf693288a28f97fdc749e67b843a' 
  AND token = 'dA8aj1XZx9p2+nj/NlLJiaPICj2y5ouZrlnzr+RDDUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}