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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3a4d400b00a87af7ac18664d91fa6b02637157819d16066e24b7f8720e46b3' 
  AND token = 'voKWSM0PmVqKQlQXoI3esPbP4laxa+k3HAKSTq/PpHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}