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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686c294b3737fd8c16ce0f5da76e8ee7f570841f63500170e3e2e2c1f84c7ea8' 
  AND token = 'c4pMFpeE6SAC6PNKhGbbl+dSOhH+M4PThkBRWWV2KwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}