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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c9d3ea8f670e6f7f54012fbb35e2df3842343405171544e44677dbdfe6e4ce' 
  AND token = 'ykmEBBfKWq8FBfBWdbqlvoUyGxXSpBbPxXf6DGLYNVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}