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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f9cc760779b508693e5e61914b5b1e6cd52d71396b1deddfc88adcc1788523' 
  AND token = 'qU5zG8WP6VP0BGYSUETyuXZWVVR3+SrPPuGBjlTcVL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}