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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9d7efa4624608c18c72dd344471ad6d420737c913a013269a81e99682d5c13' 
  AND token = 'WEK9OxmS1NeWMzNHHKUzv1RarY5IeR2kem+irsEZxlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}