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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a3263669a9a8985e949f24d3bcc8cf05520eeeaeb5de5878fe5d508023939c4' 
  AND token = '4S1GrD3//zKtECpwdyTTOrX5iMDrF4u/Jcxq3YOrTt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}