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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de2d4777a04041363f644b943f3fd1827ab8b47fae48a1abfe82d4af9fbc1ef' 
  AND token = 'jfAc2HCWOuYcSWPzryYoERPH67DZbmUJhMita8bn5vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}