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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f550e5ee0c7503822b0e69f7a80797ff0ff4790931ea4f85583b583801cfa7' 
  AND token = 'eQZYvECDBbx7m7eVq2tdg8NOkpbQ7QqFcTYg8q/BDEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}