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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3100afd958e29d854476247e7c0f5c90ea0f6218cd0d9f5338a42410c0c5a415' 
  AND token = 'qohvXV3u3I4kI1xOMoFlfAFGrXpQu4PNq9ZYTdn70m8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}