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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891a70840b473b7e661abe60a2cad35db20c014d645ea16fb44bbaf140a4f270' 
  AND token = 'eYco4VEs3fsuB1Ka9x7BedOrYwcrV0tXT8ptI/jsFmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}