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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb33386431efee4b0e7f605436fce726fd71e27f1e9e7bb09ea5ca8952c68963' 
  AND token = 'Y4VYGPNPwbUkIbhVYbhKbM9qT7ksruepDpNgrAjxX6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}