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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4efcd6e2b406275c63bd06fbf2dd0fc3ff1fef85503d6a54233c0e44df049811' 
  AND token = 'l1m7gNlG9sOaGsUjrCBwSOzzdSeyOotxYm+jMP4hC1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}