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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af8ef2d80f8ca1479a0ac9b4d51def8e2c93f86eab68e6f064289ae96db7639' 
  AND token = 'ytwz0ZAvt2PZJD84yaFrYEyX1P5Vm57zSSKuDxNTlqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}