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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408a0fb5c1f3f303ba69535f02e6b8a6dbfa2116a9f086f252fdd5e41400564a' 
  AND token = 'mW09vsqyN7u92ngC4f+wOU++rJR23lJClsWB49Shxmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}