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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5462a3e602728512cc6f0179a7c81a28ccc0e0a3a906a604a80dfb98ca357d2' 
  AND token = 'NJfwBCqIjGlnmf0S+rc6y1Psvwu4AEG7eqqxR0FwTOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}