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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3730778cadf7b856cdaf315cf280aed6cb1c0695324e09e2e0cdab2cb55f2932' 
  AND token = 'jvV4Y3dPqrjPKWsiTlNnXW298tNokcBQr75g+R3MLOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}