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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa43674a3602381064968fb29894fcced038432c2a3488a2ea4895966cf42b45' 
  AND token = '669CJfMELMA2fnuqgdNcrI+4YZKc0IG8+poAmXMPZYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}