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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b6a14a139138ac172d75f027a2ca718c48897ce1ff9141e84b6916a0c4220d' 
  AND token = 'sYbIn3/qxLHfPtLFPW0j8l23ZXke7LV65AxeS55Bex0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}