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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375c61ae01c5acf2212a3a1f4c4f08d1c5a92aaa21d6dd5f7c861229fdb6b910' 
  AND token = 'aY88hfKa6lfFi3fXqGt5uOzxBWAhYAhRzm3CjATbVsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}