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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02386f0f2f6e9365a6b0104b400713708b3de6e3269cb8416f34633e8dcd77f0' 
  AND token = 'YwAh+BwZxEFDXoUtAp4dEdGJeOEqa4dgxu/WWBxD7K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}