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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91c7adc29877a2809f7947314766b5af0ee2705d414e39e9196b64d26a259206' 
  AND token = '0OTkh89Ybv/hAZBz5D7qQA3wKDC6RA2fVmQV5CaSB74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}