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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ba72dfb2bf42339632a91b80e6a28aad242947d110b07f0019ad18bb006cebf' 
  AND token = 'R17QjO5/+R7h6UNUVqz46h/K1EoYZjBceFXf60p+VcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}