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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcf904fdf51b1f236c01ee09999c824fbf8d8c3d33361fbf3dd62ae3d0311493' 
  AND token = 'j0Zx8ueqJZnh7sN8FtKk9I3d2bQdUHDS6SGbMvRsGRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}