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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8889ce950119423511bb2e26fac4478d56dac6c823371d7d27d8d6914684c6e0' 
  AND token = 'Ssdm3Pu+p7RBir/m973rD+8oNs4zfGUVmPiPbA4Av2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}