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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86ada82a8777a31a49c15cc96d9e0ce3529dc8936b90173f4e56e478ecbb0dfa' 
  AND token = 'o0OHV55p2Wk+wB48ZyIOqfWkuMXROrVzIpCMX6tSAUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}