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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548e7e57dfa7748b0550c9ae427d93a92bda22d55b3597410a58a7d567987e91' 
  AND token = 'GISA7haLLrekw/8+/ySUv7a4DRhR/n42tF0mdrZFaTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}