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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306e76ac2886ccd7539a6dfd4eba752643559249acd56c490c80d7cc078034f4' 
  AND token = 'JQsbStw8Bw7c2H0UMPz1N3h1gZYcq6lgshLmzKjrk04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}