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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b892f72e24876ac79ee00e028f5baf918b52c203a409e49b64c0e86b47cfe0' 
  AND token = 'SGkZqJwbdfVSBPz25GbAjvz4+v2EWjE+YBUF+0e0TqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}