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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60bf08a221a164e0d2da2d72b284e5e3e5a2d5c0eb14e78da313102e11a12aed' 
  AND token = 'AK9VIgtrroSRgI+NTbXqOu5B7xwYCSYjej4EDDMd68k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}