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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5121575e329b2dde4c8cd7000cee117ed5bf70d29f934b849e9b5f4aada4613d' 
  AND token = 'LFT+X3TxU0tXn+a0KCvnt38Fmmynj6lJgKvBa7d5b0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}