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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ecdc7f22c8d02f53d8364fbb9ca9294ee1e9aa0d9997978370d496ca9b6653' 
  AND token = 'PF8CReNiGA0pLkRWCgsTWgSGLJQaKokc8BohtXjxgzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}