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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80662a2e4839c9c9346f7437b3173e69b07757b7d37549bf0e0ae329fa803b3e' 
  AND token = 'pODJRyjN4VDVshTWrdAvavp6dLgQ4xztolPsaKNRhZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}