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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc4ba1cb201c5d17bb494a7630a24bb12d0e4a19a8f918cf4e6de577c358852' 
  AND token = '+1s6rcU8XIZTRRyY7VguM+tPKtBrvFWBWzDcatmZNjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}