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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bbe24905dd10d404b0ef1daff2da33de692e51750ca04042a75acd27f95c03' 
  AND token = 'lEXydU2kcH7Hr6qSw7EBwMYCnOHnJFviDfUsM892vYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}